It may sound straight forward, but living a less comfortable life for your entire life will in tendency shorten your life. An interesting study out of Switzerland (Institute of Social and Preventive Medicine, University of Berne) compared frequency of deaths (by impairment category) with the floor that the apartments of the study subjects were located on. The majority of Swiss citizens does not own property, but rents. The amount of rent one pays depends in high-risers on the floor the apartment is situated on (think views to the mountains....). The floor someone lives on thus becomes an indicator of disposable wealth. It is interesting to note that over more than 10 years there were significant differences in mortality between people living on the ground floor and people living above the eighth floor of a building.
The authors included just over 1.5 million people living in buildings with four or more floors and found that mortality from all causes was higher in people living on the ground floor compared to those living on higher floors. An association with floor of residence was evident with causes associated with socio-economically patterned behaviours, such as smoking or diet. For example, mortality from cardiovascular and respiratory diseases declined with higher floors of residence, whereas no association was evident for prostate cancer.
For an active investor in biometric risk, there is meaningful information available, but the sources may not be what one expects.